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Class Explorer · Respiratory

Inhaled bronchodilators

Beta-2 agonists (cAMP-mediated relaxation) and muscarinic antagonists (blocking vagal tone), in short- and long-acting forms.

Members

Also in this class: Formoterol/salmeterol (LABA: never alone in asthma) · Tiotropium (LAMA) · Ipratropium (SAMA). Full pages arrive as the library grows.

Compare the members

Salbutamol
Onset
Minutes
Duration
4-6 h
Role
Reliever (SABA)

Shared across the class

Indications
Asthma and COPD per stepwise guidelines
Adverse effects
Tremor, tachycardia (beta agonists) · Dry mouth, urinary retention (antimuscarinics)
Contraindications
LABA monotherapy in asthma (black-box lesson)
Monitoring
Reliever use frequency · Inhaler technique at every touchpoint · Device suitability (hand strength, inspiratory flow)

What makes each agent different

  • SABA relieves; LABA maintains; LAMA maintains via the other lever. The acronyms are duration plus receptor.
  • In asthma, a LABA must live inside an ICS combination; in COPD it may stand alone.

The best inhaler is the one this patient can actually use; device choice is a clinical decision.

Last reviewed 2026-08-15 · Goodman & Gilman's The Pharmacological Basis of Therapeutics, 14th ed.